Chicken Journal Club (Bible hour)


Paper Schedule 2013 (for Vintage Literature click here)


Tuesday, March 8th, 2016 - Madeleine

Ruminococcus bromii is a keystone species for the degradation of resistant starch in the human colon.
Ze X, Duncan SH, Louis P, Flint HJ.
ISME J. 2012 Aug;6(8):1535-43. doi: 10.1038/ismej.2012.4. Epub 2012 Feb 16.
PubMed

∆ go to top of page

Tuesday, Feburary 23rd, 2016 - Stephanie

Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing.
Johansson-Lindbom B, Svensson M, Pabst O, Palmqvist C, Marquez G, Förster R, Agace WW.
J Exp Med. 2005 Oct 17;202(8):1063-73. Epub 2005 Oct 10.
PubMed

∆ go to top of page

Tuesday, January 26th, 2016 - Sandra

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification.
Petersen-Mahrt SK, Harris RS, Neuberger MS.
Nature. 2002 Jul 4;418(6893):99-103.
PubMed

∆ go to top of page

Tuesday, January 12th, 2016 - Marcel

ß-adrenergic stimulation increases macrophage CD14 expression and E. coli phagocytosis through PKA signaling mechanisms.
Muthu K, He LK, Szilagyi A, Strotmon P, Gamelli RL, Shankar R
J Leukoc Biol. 2010 Oct;88(4):715-24. doi: 10.1189/jlb.0410186. Epub 2010 Jul 19.
PubMed

∆ go to top of page

Tuesday, November 17th, 2015 - Anna

The lymph nodes draining the small intestine and colon are anatomically separate and immunologically distinct.
Houston SA, Cerovic V, Thomson C, Brewer J, Mowat AM, Milling S.
Mucosal Immunol. 2015 Sep 2. doi: 10.1038/mi.2015.77. [Epub ahead of print]
PubMed

∆ go to top of page

Tuesday, November 3rd, 2015 - Yasu

CRISPR-Cas systems for editing, regulating and targeting genomes.
Sander JD, Joung JK.
Nat Biotechnol. 2014 Apr;32(4):347-55. doi: 10.1038/nbt.2842. Epub 2014 Mar 2.
PubMed

∆ go to top of page

Tuesday, October 20th, 2015 - Francesca

Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.
Vanden Berghe T, Hulpiau P, Martens L, Vandenbroucke RE, Van Wonterghem E, Perry SW, Bruggeman I, Divert T, Choi SM, Vuylsteke M, Shestopalov VI, Libert C, Vandenabeele P.
Immunity. 2015 Jul 21;43(1):200-9. doi: 10.1016/j.immuni.2015.06.011. Epub 2015 Jul 7.
PubMed

∆ go to top of page

Tuesday, September 24th, 2015 - Mercedes

Flow cytometry APC-tandem dyes are degraded through a cell-dependent mechanism.
Le Roy C, Varin-Blank N, Ajchenbaum-Cymbalista F, Letestu R.
Cytometry A. 2009 Oct;75(10):882-90. doi: 10.1002/cyto.a.20774.
PubMed

∆ go to top of page
Tuesday, September 8th, 2015 - Stephanie

Symbiotic bacteria direct expression of an intestinal bactericidal lectin.
Cash HL, Whitham CV, Behrendt CL, Hooper LV.
Science. 2006 Aug 25;313(5790):1126-30.
PubMed

∆ go to top of page
Tuesday, June 16th, 2015 - Madeleine

A direct PCR approach to accelerate analyses of human-associated microbial communities.
Flores GE, Henley JB, Fierer N.
APLoS One. 2012;7(9):e44563. doi: 10.1371/journal.pone.0044563. Epub 2012 Sep 4.
PubMed

∆ go to top of page
Tuesday, June 2nd, 2015 - Sandra

Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine.
Lindner C, Wahl B, Föhse L, Suerbaum S, Macpherson AJ, Prinz I, Pabst O.
J Exp Med. 2012 Feb 13;209(2):365-77. doi: 10.1084/jem.20111980. Epub 2012 Jan 16.
PubMed

∆ go to top of page
Tuesday, May 12th, 2015 - Marcel

Direct secretory effect of interleukin-1 via type I receptors in human colonic mucous epithelial cells (HT29-C1.16E).
Jarry A, Vallette G, Branka JE, Laboisse C.
Gut. 1996 Feb;38(2):240-2.
PubMed

∆ go to top of page
Tuesday, May 5th, 2015 - William

Bacterial translocation from the gastrointestinal tract of athymic (nu/nu) mice.
Owens WE, Berg RD.
Infect Immun. 1980 Feb;27(2):461-7.
PubMed

∆ go to top of page
Tuesday, April 14th, 2015 - Yasu

Graphical Perception: Theory, Experimentation, and Application to the Development of Graphical Methods
William S. Cleveland and Robert McGill
Journal of the American Statistical Association
Vol. 79, No. 387 (Sep., 1984), pp. 531-554
Journal website

Graphical perception and graphical methods for analyzing scientific data.
Cleveland WS, McGill R.
Science. 1985 Aug 30;229(4716):828-33.
PubMed

∆ go to top of page
Tuesday, March 31st, 2015 - Anna

CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance.
Niess JH, Brand S, Gu X, Landsman L, Jung S, McCormick BA, Vyas JM, Boes M, Ploegh HL, Fox JG, Littman DR, Reinecker HC.
Science. 2005 Jan 14;307(5707):254-8.
PubMed

∆ go to top of page

Tuesday, March 24th, 2015 - Li Hai

Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells.
Mora JR, Iwata M, Eksteen B, Song SY, Junt T, Senman B, Otipoby KL, Yokota A, Takeuchi H, Ricciardi-Castagnoli P, Rajewsky K, Adams DH, von Andrian UH.
Science. 2006 Nov 17;314(5802):1157-60.
PubMed

∆ go to top of page
Tuesday, March 3rd, 2015 - Francesca

Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity.
Markle JG, Frank DN, Mortin-Toth S, Robertson CE, Feazel LM, Rolle-Kampczyk U, von Bergen M, McCoy KD, Macpherson AJ, Danska JS.
Science. 2013 Mar 1;339(6123):1084-8. doi: 10.1126/science.1233521. Epub 2013 Jan 17.
PubMed

∆ go to top of page
Tuesday, Febrary 3rd, 2015 - Mercedes

Characterization of diet-dependent metabolic serotypes: analytical and biological variability issues in rats.
Vigneau-Callahan KE1, Shestopalov AI, Milbury PE, Matson WR, Kristal BS.
J Nutr. 2001 Mar;131(3):924S-932S.
PubMed

∆ go to top of page

Tuesday, January 20th, 2015 - Kathleen

Reagent and laboratory contamination can critically impact sequence-based microbiome analyses.
Salter SJ, Cox MJ, Turek EM, Calus ST, Cookson WO, Moffatt MF, Turner P, Parkhill J, Loman NJ, Walker AW.
BMC Biol. 2014 Nov 12;12:87. doi: 10.1186/s12915-014-0087-z.
PubMed

∆ go to top of page
Tuesday, December 16th, 2014 - Sandra

Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site.
Bostrom J, Yu SF, Kan D, Appleton BA, Lee CV, Billeci K, Man W, Peale F, Ross S, Wiesmann C, Fuh G.
Science. 2009 Mar 20;323(5921):1610-4. doi: 10.1126/science.1165480.
PubMed 

∆ go to top of page
Tuesday, December 2nd, 2014 - Yasmin

Differential secretion of cytokines.
Moqbel R, Coughlin JJ.
Sci STKE. 2006 Jun 6;2006(338):pe26.
PubMed

∆ go to top of page
Tuesday, November 18th, 2014 - William

Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.
Roger T, Froidevaux C, Le Roy D, Reymond MK, Chanson AL, Mauri D, Burns K, Riederer BM, Akira S, Calandra T.
Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2348-52. doi: 10.1073/pnas.0808146106. Epub 2009 Jan 30.
PubMed

∆ go to top of page

Wednesday, November 5th, 2014 - Yasuhiro

Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5.
Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi S, Srinivasan S, Sitaraman SV, Knight R, Ley RE, Gewirtz AT.
Science. 2010 Apr 9;328(5975):228-31. doi: 10.1126/science.1179721. Epub 2010 Mar 4.
PubMed

∆ go to top of page

Tuesday, September 30th, 2014 - Li Hai

Molecular analysis of commensal host-microbial relationships in the intestine.
Hooper LV1, Wong MH, Thelin A, Hansson L, Falk PG, Gordon JI.
Science. 2001 Feb 2;291(5505):881-4.
PubMed

∆ go to top of page

Tuesday, September 16th, 2014 - Francesca

Autoantigen recognition is required for recruitment of IGRP(206-214)-autoreactive CD8+ T cells but is dispensable for tolerance.
Wang J, Tsai S, Han B, Tailor P, Santamaria P.
J Immunol. 2012 Sep 15;189(6):2975-84. doi: 10.4049/jimmunol.1201787. Epub 2012 Aug 20.
PubMed

∆ go to top of page

Tuesday, August 12th, 2014 - Anna

Simultaneous amplification and detection of specific DNA sequences.
Higuchi R1, Dollinger G, Walsh PS, Griffith R.
Biotechnology (N Y). 1992 Apr;10(4):413-7.
PubMed

∆ go to top of page

Tuesday, July 22th, 2014 - Julien

Systems biology: a brief overview.
Kitano H.
Science. 2002 Mar 1;295(5560):1662-4.
PubMed

∆ go to top of page

Tuesday, July 8th, 2014 - Mercedes

Spectrophotometer: new instrument for ultrarapid cell analysis.
Kamentsky LA, Melamed MR, Derman H.
Science. 1965 Oct 29;150(3696):630-1.
PubMed

∆ go to top of page

Tuesday, June 17th, 2014 - Sandra

High-throughput sequencing of the zebrafish antibody repertoire.
Weinstein JA1, Jiang N, White RA 3rd, Fisher DS, Quake SR.
Science. 2009 May 8;324(5928):807-10. doi: 10.1126/science.1170020.
PubMed - PDF

∆ go to top of page

Tuesday, June 10th, 2014 - Stephanie

Requirement for RORgamma in thymocyte survival and lymphoid organ development.
Sun Z, Unutmaz D, Zou YR, Sunshine MJ, Pierani A, Brenner-Morton S, Mebius RE, Littman DR.
Science. 2000 Jun 30;288(5475):2369-73.
PubMed - PDF

∆ go to top of page

Tuesday, May 27th, 2014 - Yasmin

Unresponsiveness of MyD88-deficient mice to endotoxin.
Kawai T, Adachi O, Ogawa T, Takeda K, Akira S.
Immunity. 1999 Jul;11(1):115-22.
PubMed - PDF

Interleukin-6: possible biological roles during exercise.
Reihmane D, Dela F.
Eur J Sport Sci. 2014;14(3):242-50. doi: 10.1080/17461391.2013.776640. Epub 2013 Mar 11.
PubMed - PDF

∆ go to top of page

Tuesday, May 13th, 2014 - William

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43.
Maslowski KM, Vieira AT, Ng A, Kranich J, Sierro F, Yu D, Schilter HC, Rolph MS, Mackay F, Artis D, Xavier RJ, Teixeira MM, Mackay CR.
Nature. 2009 Oct 29;461(7268):1282-6. doi: 10.1038/nature08530.
PubMed - PDF

∆ go to top of page

Tuesday, April 22nd, 2014 - Li Hai

Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.
Tsuji M, Suzuki K, Kitamura H, Maruya M, Kinoshita K, Ivanov II, Itoh K, Littman DR, Fagarasan S.
Immunity. 2008 Aug 15;29(2):261-71. doi: 10.1016/j.immuni.2008.05.014. Epub 2008 Jul 24.
PubMed - PDF

∆ go to top of page

Tuesday, March 25th, 2014 - Francesca

Rapid secretion of interleukin-1beta by microvesicle shedding.
MacKenzie A, Wilson HL, Kiss-Toth E, Dower SK, North RA, Surprenant A.
Immunity. 2001 Nov;15(5):825-35.
PubMed - PDF

∆ go to top of page

Tuesday, March 4th, 2014 - Yasuhiro

Points of significance: Power and sample size
Martin Krzywinski  & Naomi Altman
Nature Methods 10, 1139–1140 (2013) doi:10.1038/nmeth.2738
(Pubmed is not yet uploaded)

∆ go to top of page

Tuesday, January 28th, 2014 - Mercedes

Salmonella gut invasion involves TTSS-2-dependent epithelial traversal, basolateral exit, and uptake by epithelium-sampling lamina propria phagocytes.
Müller AJ, Kaiser P, Dittmar KE, Weber TC, Haueter S, Endt K, Songhet P, Zellweger C, Kremer M, Fehling HJ, Hardt WD.
Cell Host Microbe. 2012 Jan 19;11(1):19-32. doi: 10.1016/j.chom.2011.11.013.
PubMed - PDF

∆ go to top of page

Tuesday, January 14th, 2014 - Sandra

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting.
Gu H, Zou YR, Rajewsky K.
Cell. 1993 Jun 18;73(6):1155-64.
PubMed - PDF

∆ go to top of page

Tuesday, December 10th, 2013 - Stephanie

Adaptive immune features of natural killer cells.
Sun JC, Beilke JN, Lanier LL.
Nature. 2009 Jan 29;457(7229):557-61. doi: 10.1038/nature07665. Epub 2009 Jan 11.
PubMed - PDF

∆ go to top of page

Tuesday, November 26th, 2013 - William

The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota.
Round JL, Lee SM, Li J, Tran G, Jabri B, Chatila TA, Mazmanian SK.
Science. 2011 May 20;332(6032):974-7. doi: 10.1126/science.1206095. Epub 2011 Apr 21.
PubMed - PDF

∆ go to top of page

Tuesday, November 19th, 2013 - Yasmin

Microbiota-mediated colonization resistance against intestinal pathogens.
Buffie CG, Pamer EG.
Nat Rev Immunol. 2013 Nov;13(11):790-801. doi: 10.1038/nri3535. Epub 2013 Oct 7.
PubMed - PDF (password)

∆ go to top of page

Tuesday, November 5th, 2013 - Melissa

B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development.
Lam KP, Rajewsky K.
J Exp Med. 1999 Aug 16;190(4):471-7.
PubMed - PDF (password)

∆ go to top of page

Tuesday, October 15th, 2013 - Li Hai

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria.
Johansson ME, Phillipson M, Petersson J, Velcich A, Holm L, Hansson GC.
Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15064-9. doi: 10.1073/pnas.0803124105. Epub 2008 Sep 19.
PubMed - PDF (password)

∆ go to top of page

Tuesday, October 1st, 2013 - Francesca

The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation.
Subramanian N, Natarajan K, Clatworthy MR, Wang Z, Germain RN.
Cell. 2013 Apr 11;153(2):348-61. doi: 10.1016/j.cell.2013.02.054.
PubMed - PDF (password)

∆ go to top of page

Tuesday, September 17th, 2013 - Peter

Crohn's disease.
Baumgart DC, Sandborn WJ.
Lancet. 2012 Nov 3;380(9853):1590-605. doi: 10.1016/S0140-6736(12)60026-9. Epub 2012 Aug 20.
PubMed - PDF (password)

∆ go to top of page

Tuesday, September 3rd, 2013 - Jamie

Cytotoxic T-cell memory without antigen.
Lau LL, Jamieson BD, Somasundaram T, Ahmed R.
Nature. 1994 Jun 23;369(6482):648-52.
PubMed - PDF (password)

T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation.
Jackson SH, Devadas S, Kwon J, Pinto LA, Williams MS.
Nat Immunol. 2004 Aug;5(8):818-27. Epub 2004 Jul 18.
PubMed - PDF (password)

∆ go to top of page

Tuesday, August 20th, 2013 - Yasuhiro

A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria.
Macpherson AJ, Gatto D, Sainsbury E, Harriman GR, Hengartner H, Zinkernagel RM.
Science. 2000 Jun 23;288(5474):2222-6.
PubMed - PDF (password)

Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria.
Macpherson AJ, Uhr T.
Science. 2004 Mar 12;303(5664):1662-5.
PubMed - PDF (password)

∆ go to top of page

Tuesday, July 9th, 2013 - William

Retinoic acid imprints gut-homing specificity on T cells.
Iwata M, Hirakiyama A, Eshima Y, Kagechika H, Kato C, Song SY.
Immunity. 2004 Oct;21(4):527-38.
PubMed - PDF (password)

∆ go to top of page

Tuesday, June 25th, 2013 - Yasmin

The role of the immune system in governing host-microbe interactions in the intestine.
Brown EM, Sadarangani M, Finlay BB.
Nat Immunol. 2013 Jun 18;14(7):660-7. doi: 10.1038/ni.2611.
PubMed - PDF (password)

Commensal bacteria at the interface of host metabolism and the immune system.
Brestoff JR, Artis D.
Nat Immunol. 2013 Jun 18;14(7):676-84. doi: 10.1038/ni.2640.
PubMed - PDF (password)

∆ go to top of page

Tuesday, June 11th, 2013 - Melissa

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL.
Litinskiy MB, Nardelli B, Hilbert DM, He B, Schaffer A, Casali P, Cerutti A.
Nat Immunol. 2002 Sep;3(9):822-9. Epub 2002 Aug 5.
PubMed - PDF (password) - News & Views 

∆ go to top of page

Tuesday, May 28th, 2013 - Li Hai

Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota.
Stecher B, Robbiani R, Walker AW, Westendorf AM, Barthel M, Kremer M, Chaffron S, Macpherson AJ, Buer J, Parkhill J, Dougan G, von Mering C, Hardt WD.
PLoS Biol. 2007 Oct;5(10):2177-89.
PubMed - PDF (password)

∆ go to top of page

Tuesday, May 14th, 2013 - Francesca

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf.
Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP, Roose-Girma M, Erickson S, Dixit VM.
Nature. 2004 Jul 8;430(6996):213-8. Epub 2004 Jun 9.
PubMed - PDF (password)

∆ go to top of page

Tuesday, April 30th, 2013 - Yasuhiro

Control of early viral and bacterial distribution and disease by natural antibodies.
Ochsenbein AF, Fehr T, Lutz C, Suter M, Brombacher F, Hengartner H, Zinkernagel RM.
Science. 1999 Dec 10;286(5447):2156-9.
PubMed - PDF (password)

∆ go to top of page

Tuesday, April 16th, 2013 - Sandra

Sequencing technologies - the next generation.
Metzker ML.
Nat Rev Genet. 2010 Jan;11(1):31-46. doi: 10.1038/nrg2626. Epub 2009 Dec 8.
PubMed - PDF Review (password) - PDF Review 2 (password)

∆ go to top of page

Tuesday, April 2nd, 2013 - Julia

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense.
Satoh-Takayama N, Vosshenrich CA, Lesjean-Pottier S, Sawa S, Lochner M, Rattis F, Mention JJ, Thiam K, Cerf-Bensussan N, Mandelboim O, Eberl G, Di Santo JP.
Immunity. 2008 Dec 19;29(6):958-70. doi: 10.1016/j.immuni.2008.11.001. Epub 2008 Dec 11.
PubMed - PDF (password) - supplementary material

∆ go to top of page

Tuesday, March 19th, 2013 - Yasmin

Eosinophils: changing perspectives in health and disease.
Rosenberg HF, Dyer KD, Foster PS.
Nat Rev Immunol. 2013 Jan;13(1):9-22. doi: 10.1038/nri3341. Epub 2012 Nov 16.
PubMed - PDF (password)

∆ go to top of page

Tuesday, March 12th, 2013 - William

Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut.
Fritz JH, Rojas OL, Simard N, McCarthy DD, Hapfelmeier S, Rubino S, Robertson SJ, Larijani M, Gosselin J, Ivanov II, Martin A, Casellas R, Philpott DJ, Girardin SE, McCoy KD, Macpherson AJ, Paige CJ, Gommerman JL.
Nature. 2011 Dec 11;481(7380):199-203. doi: 10.1038/nature10698.
PubMed - PDF (password)

∆ go to top of page

Tuesday, February 26th, 2013 - Melissa

Enterotypes of the human gut microbiome.
Arumugam M, Raes J, Pelletier E, Le Paslier D, Yamada T, Mende DR, Fernandes GR, Tap J, Bruls T, Batto JM, Bertalan M, Borruel N, Casellas F, Fernandez L, Gautier L, Hansen T, Hattori M, Hayashi T, Kleerebezem M, Kurokawa K, Leclerc M, Levenez F, Manichanh C, Nielsen HB, Nielsen T, Pons N, Poulain J, Qin J, Sicheritz-Ponten T, Tims S, Torrents D, Ugarte E, Zoetendal EG, Wang J, Guarner F, Pedersen O, de Vos WM, Brunak S, Doré J; MetaHIT Consortium, Antolín M, Artiguenave F, Blottiere HM, Almeida M, Brechot C, Cara C, Chervaux C, Cultrone A, Delorme C, Denariaz G, Dervyn R, Foerstner KU, Friss C, van de Guchte M, Guedon E, Haimet F, Huber W, van Hylckama-Vlieg J, Jamet A, Juste C, Kaci G, Knol J, Lakhdari O, Layec S, Le Roux K, Maguin E, Mérieux A, Melo Minardi R, M'rini C, Muller J, Oozeer R, Parkhill J, Renault P, Rescigno M, Sanchez N, Sunagawa S, Torrejon A, Turner K, Vandemeulebrouck G, Varela E, Winogradsky Y, Zeller G, Weissenbach J, Ehrlich SD, Bork P.
Nature. 2011 May 12;473(7346):174-80. doi: 10.1038/nature09944. Epub 2011 Apr 20.
PubMed - PDF (password)

∆ go to top of page

Tuesday, February 5th, 2013 - Li Hai

Non-haemolytic beta-amino-acid oligomers.
Porter EA, Wang X, Lee HS, Weisblum B, Gellman SH.
Nature. 2000 Apr 6;404(6778):565. No abstract available. Erratum in: Nature 2000 May 18;405(6784):298.
PubMed - PDF (password)

∆ go to top of page

Tuesday, January 22nd, 2013 - Mercedes

Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies.
Prussin C, Metcalfe DD.
J Immunol Methods. 1995 Dec 15;188(1):117-28.
PubMed - PDF (password)

∆ go to top of page


Previously discussed papers (2011-2012)

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity.
Neill DR, Wong SH, Bellosi A, Flynn RJ, Daly M, Langford TK, Bucks C, Kane CM, Fallon PG, Pannell R, Jolin HE, McKenzie AN.
Nature. 2010 Apr 29;464(7293):1367-70. doi: 10.1038/nature08900. Epub 2010 Mar 3.
PubMed - PDF (password)

∆ go to top of page

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.
Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR.
Cell. 2006 Sep 22;126(6):1121-33.
PubMed - PDF (password)

∆ go to top of page

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.
Fontenot JD, Gavin MA, Rudensky AY.
Nat Immunol. 2003 Apr;4(4):330-6. Epub 2003 Mar 3.
PubMed - PDF (password)

∆ go to top of page

Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora.
Fagarasan S, Muramatsu M, Suzuki K, Nagaoka H, Hiai H, Honjo T.
Science. 2002 Nov 15;298(5597):1424-7.
PubMed - PDF (password)

∆ go to top of page

Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene.
Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, Du X, Birdwell D, Alejos E, Silva M, Galanos C, Freudenberg M, Ricciardi-Castagnoli P, Layton B, Beutler B.
Science. 1998 Dec 11;282(5396):2085-8.
PubMed - PDF (password)

∆ go to top of page

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults.
Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA.
Cell. 1996 Sep 20;86(6):973-83.
PubMed - PDF (password)

∆ go to top of page

T cell receptor antagonist peptides induce positive selection.
Hogquist KA, Jameson SC, Heath WR, Howard JL, Bevan MJ, Carbone FR.
Cell. 1994 Jan 14;76(1):17-27.
PubMed - PDF (password)

∆ go to top of page

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.
Saiki RK, Gelfand DH, Stoffel S, Scharf SJ, Higuchi R, Horn GT, Mullis KB, Erlich HA.
Science. 1988 Jan 29;239(4839):487-91.
PubMed - PDF (password)

∆ go to top of page

T cell tolerance by clonal elimination in the thymus.
Kappler JW, Roehm N, Marrack P.
Cell. 1987 Apr 24;49(2):273-80.
PubMed - PDF (password)

∆ go to top of page

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.
Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL.
J Immunol. 1986 Apr 1;136(7):2348-57.
PubMed - PDF (password)

∆ go to top of page

Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.
Saiki RK, Scharf S, Faloona F, Mullis KB, Horn GT, Erlich HA, Arnheim N.
Science. 1985 Dec 20;230(4732):1350-4.
PubMed - PDF (password)

∆ go to top of page

Isolation of human T-cell leukemia virus in acquired immune deficiency syndrome (AIDS).
Gallo RC, Sarin PS, Gelmann EP, Robert-Guroff M, Richardson E, Kalyanaraman VS, Mann D, Sidhu GD, Stahl RE, Zolla-Pazner S, Leibowitch J, Popovic M.
Science. 1983 May 20;220(4599):865-7.
PubMed - PDF (password)

∆ go to top of page

Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).
Barré-Sinoussi F, Chermann JC, Rey F, Nugeyre MT, Chamaret S, Gruest J, Dauguet C, Axler-Blin C, Vézinet-Brun F, Rouzioux C, Rozenbaum W, Montagnier L.
Science. 1983 May 20;220(4599):868-71.
PubMed - PDF (password)

∆ go to top of page

The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes.
Maki R, Roeder W, Traunecker A, Sidman C, Wabl M, Raschke W, Tonegawa S.
Cell. 1981 May;24(2):353-65.
PubMed - PDF (password)

∆ go to top of page

The origin and antigen-dependent distribution of IgA-containing cells in the intestine.
Husband AJ, Gowans JL.
J Exp Med. 1978 Nov 1;148(5):1146-60.
PubMed - PDF (password)

∆ go to top of page

Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions.
Hozumi N, Tonegawa S.
Proc Natl Acad Sci U S A. 1976 Oct;73(10):3628-32.
PubMed - PDF (password)

∆ go to top of page

Continuous cultures of fused cells secreting antibody of predefined specificity.
Köhler G, Milstein C.
Nature. 1975 Aug 7;256(5517):495-7.
PubMed - PDF (password)

∆ go to top of page

Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis.
Zinkernagel RM, Doherty PC.
Nature. 1974 Oct 11;251(5475):547-8.
PubMed - PDF (password)

∆ go to top of page

H-2 compatibility is required for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus.
Doherty PC, Zinkernagel RM.
J Exp Med. 1975 Feb 1;141(2):502-7.
PubMed - PDF (password)

∆ go to top of page

Epithelial cell specialization within human Peyer's patches: an ultrastructural study of intestinal lymphoid follicles.
Owen RL, Jones AL.
Gastroenterology. 1974 Feb;66(2):189-203.
PubMed - PDF (password)

∆ go to top of page

The covalent structure of an entire gamma G immunoglobulin molecule (1969).
Edelman GM, Cunningham BA, Gall WE, Gottlieb PD, Rutishauser U, Waxdal MJ.
Reprinted in J Immunol. 2004 Nov 1;173(9):5335-42.
PubMed - PDF (password)

∆ go to top of page


  •  
  •  
  •  
  •  
© 2012-2015 Gastroenterology & Mucosal Immunology, Bern, Switzerland
Swiss Web Design